This condensation is needed to allow the chromosomes to move along the mitotic spindle without becoming tangled or broken during their distribution to daughter cells. DNA in this highly condensed state can no longer be transcribed, so all RNA synthesis stops during mitosis.
Why do chromosomes condense during mitosis?
Chromosomes condense before mitosis to allow them the ability to move smoothly, without becoming entangled and breaking. (So, they are conveniently packaged for cell division, in which the chromosomes must move to both poles of the cell.)
What is the purpose of chromosome condensation?
Mitotic chromosome condensation is an essential cellular function ensuring proper compaction and segregation of sister chromatids during cell division.
Do chromosomes condense during mitosis?
Conclusion. Mitosis is the process of nuclear division, which occurs just prior to cell division, or cytokinesis. During this multistep process, cell chromosomes condense and the spindle assembles.
What happens if chromosomes dont condense?
If they do not align correctly, they cannot move individually to opposite poles in the later phases of mitosis, and the result will be one cell with extra chromosomes and a daughter cell with missing chromosomes. These mutations can lead to harmful results such as cell death, organic disease or cancer.
What happens when a chromosome condenses?
Nuclear Changes in Prophase
Chromosome condensation, the landmark event at the onset of prophase, often begins in isolated patches of chromatin at the nuclear periphery. Later, chromosome condense into two threads termed sister chromatids that are closely paired along their entire lengths.
What is initiation of condensation of chromosomal material?
Figure 1: Chromatin condensation changes during the cell cycle. During interphase (1), chromatin is in its least condensed state and appears loosely distributed throughout the nucleus. Chromatin condensation begins during prophase (2) and chromosomes become visible.
Does chromatin condense into chromosomes in meiosis?
Meiosis I, the first meiotic division, begins with prophase I. During prophase I, the complex of DNA and protein known as chromatin condenses to form chromosomes. The pairs of replicated chromosomes are known as sister chromatids, and they remain joined at a central point called the centromere.