Which is an agent that cause a mutation in DNA or chromosomes?

A mutagen is defined as an agent that causes irreversible and heritable changes (mutations) in the cellular genetic material, deoxyribonucleic acid (DNA).

What causes mutations in chromosomes?

Chromosome structure mutations are alterations that affect whole chromosomes and whole genes rather than just individual nucleotides. These mutations result from errors in cell division that cause a section of a chromosome to break off, be duplicated or move onto another chromosome.

What chemical agents can cause mutations in DNA?

The most commonly used chemical mutagens are alkylating agents such as ethylmethane sulfonate and N-methyl-N-nitrosourea that induce point mutations in DNA.

What is the most common cause of mutation to DNA?

Natural exposure of an organism to certain environmental factors, such as ultraviolet light and chemical carcinogens (e.g., aflatoxin B1), also can cause mutations. A common cause of spontaneous point mutations is the deamination of cytosine to uracil in the DNA double helix.

What is an example of chromosomal mutation?

Types of Changes in DNA

Class of Mutation Type of Mutation Human Disease(s) Linked to This Mutation
Chromosomal mutation Deletion Cri du chat syndrome
Duplication Some cancers
Translocation One form of leukemia
Copy number variation Gene amplification Some breast cancers

What causes a deletion mutation?

A deletion mutation occurs when a wrinkle forms on the DNA template strand and subsequently causes a nucleotide to be omitted from the replicated strand (Figure 3). Figure 3: In a deletion mutation, a wrinkle forms on the DNA template strand, which causes a nucleotide to be omitted from the replicated strand.

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What are the agents of mutation?

The chemical or physical agents that cause mutations are called mutagens. Examples of physical mutagens are ultraviolet (UV) and gamma radiation.

What are mutation causing agents called?

A mutagen is defined as an agent that causes irreversible and heritable changes (mutations) in the cellular genetic material, deoxyribonucleic acid (DNA).

What is the difference between a mutation and a mutagen?

A Mutation occurs when a DNA gene is damaged or changed in such a way as to alter the genetic message carried by that gene. A Mutagen is an agent of substance that can bring about a permanent alteration to the physical composition of a DNA gene such that the genetic message is changed.

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