The frequency of heterozygous individuals. Answer: The frequency of heterozygous individuals is equal to 2pq. In this case, 2pq equals 0.32, which means that the frequency of individuals heterozygous for this gene is equal to 32% (i.e. 2 (0.8)(0.2) = 0.32).

## What term in the Hardy-Weinberg equation is used to calculate the frequency of the heterozygote?

where p is the frequency of the “A” allele and q is the frequency of the “a” allele in the population. In the equation, p^{2} represents the frequency of the homozygous genotype AA, q^{2} represents the frequency of the homozygous genotype aa, and **2pq** represents the frequency of the heterozygous genotype Aa.

## What is the highest frequency of heterozygotes under Hardy-Weinberg equilibrium?

Population heterozygosity (the frequency of heterozygotes) is highest when **p = q = 0.5**. Rare alleles are found primarily in heterozygotes, as they must be, given that q^{2} is much smaller than 2pq when q is near zero, and p^{2} is much smaller than 2pq when p is near zero.

## Are heterozygotes favored in Hardy-Weinberg?

The homozygous dominant does not protect against malaria, so therefore **heterozygosity is favored**.

## How do you find the Hardy-Weinberg allele frequency?

To calculate the allelic frequencies we simply **divide the number of S or F alleles by the total number of alleles**: 94/128 = 0.734 = p = frequency of the S allele, and 34/128 = 0.266 = q = frequency of the F allele.

## Why is there a 2 in 2pq?

The term p2 represents **the frequency of dominant homozygotes (AA)** and the term q2 represents the frequency of recessive homozygotes (aa). p represents the allele frequency of allele A, and q represents the allele frequency of the allele a.

## How do you find the frequency of heterozygotes in a population?

To determine q, which is the frequency of the recessive allele in the population, simply **take the square root of q ^{2}** which works out to be 0.632 (i.e. 0.632 x 0.632 = 0.4).

## Does inbreeding violate Hardy-Weinberg?

Inbreeding – How does it affect a population? In a small population, the sampling of gametes and fertilization to create zygotes causes **random error** in allele frequencies. This results in a deviation from the Hardy-Weinberg Equilibrium. This deviation is larger at small sample sizes and smaller at large sample sizes.

## Which factor does not affect Hardy-Weinberg Equilibrium?

According to the Hardy Weinberg law, the allele and genotype frequencies in a population remain constant under absence of factors responsible for evolution. These factors are namely **mutation, recombination, gene migration, genetic drift and natural selection**.

## How do you know if it’s in Hardy-Weinberg Equilibrium?

To know if a population is in Hardy-Weinberg Equilibrium scientists **have to observe at least two generations**. If the allele frequencies are the same for both generations then the population is in Hardy-Weinberg Equilibrium.