Down syndrome is a genetic disorder that can affect many different parts of the body. An extra part or whole Chromosome 21 is the cause of Down syndrome. It is the most common chromosomal abnormality. This syndrome can affect the heart, the brain, the hormone system and the skeleton.
How does Down syndrome affect the skeletal system?
Several musculoskeletal abnormalities are associated with Down syndrome, including hypermobility of the joints, as well as low bone density, resulting in frequent fractures of both long bones & vertebral bodies in this population. Hypermobility is a combined effect of muscle hypotonia and excessive ligamentous laxity.
How does Down syndrome affect the central nervous system?
Down’s syndrome has manifestations in many systems. The syndrome has many neurological complications, which include structural changes, mental retardation, young-onset Alzheimer’s disease, strokes and basal ganglia damage. Epileptic seizures are more prevalent in Down’s syndrome patients than in the general population.
What is Down syndrome and how does it affect you?
Down syndrome varies in severity among individuals, causing lifelong intellectual disability and developmental delays. It’s the most common genetic chromosomal disorder and cause of learning disabilities in children. It also commonly causes other medical abnormalities, including heart and gastrointestinal disorders.
What part of the body does Down syndrome mostly affect?
Down syndrome, the most common chromosome-related genetic condition in the U.S., affects development of the brain and body.
Can a Down syndrome child look normal?
Some of the children with Mosaic Down syndrome that we know do not actually look as if they have Down syndrome – the usual physical features are not obvious. This raises some important and difficult social issues and identity issues for both parents and children, which parents have discussed with us.
Why is Down syndrome not curable?
Down syndrome is a random occurrence in nature. It has no cure or prevention measures. Down syndrome is not a disease, disorder, defect or medical condition and therefore does not require treatment, prevention or a cure.
Is Down syndrome a disability?
Down syndrome is the most frequent chromosomal cause of mild to moderate intellectual disability, and it occurs in all ethnic and economic groups. The degree of intellectual disability in people with Down syndrome varies but is usually mild to moderate.
How does Down syndrome affect the endocrine system?
Children with Down syndrome, or Trisomy 21, have a higher likelihood of developing endocrine disorders than the general population. Hypothyroidism is the most common endocrine disorder in Down syndrome. About 10 percent of children with Down syndrome are diagnosed with congenital or acquired hypothyroidism.