The sickle cell anemia trait is found on a recessive allele of the hemoglobin gene. This means that you must have two copies of the recessive allele — one from your mother and one from your father — to have the condition. People who have one dominant and one recessive copy of the allele won’t have sickle cell anemia.
Is Sickle Cell Anemia recessive or dominant?
In most situations, individuals who are heterozygous for sickle-cell anemia are phenotypically normal. Under these circumstances, sickle-cell disease is a recessive trait. Individuals who are homozygous for the sickle-cell allele (ss), however, may have sickling crises that require hospitalization.
Is Sickle Cell Anemia homozygous or heterozygous?
Sickle cell anemia is an autosomal homozygous (hemoglobin SS or HgSS) recessive trait characterized by RBCs that become sickle (crescent)-shaped when deoxygenated.
Can 2 sickle cell carriers get married?
When both individuals are sickle cell carriers, the church discourages them from marrying. Some church denominations, especially in Enugu state, go further and refuse to wed couples when both individuals are sickle cell carriers.
Is Sickle cell anemia more common in males or females?
The male-to-female ratio is 1:1. No sex predilection exists, since sickle cell anemia is not an X-linked disease.
What is AA in sickle cell?
Like most genes, individuals inherit one from each parent. Examples: If one parent has sickle cell anemia (SS) and the other parent has normal (AA) blood, all of the children will have sickle cell trait.
What should sickle cell patients avoid?
avoid very strenuous exercise – people with sickle cell disease should be active, but intense activities that cause you to become seriously out of breath are best avoided. avoid alcohol and smoking – alcohol can cause you to become dehydrated and smoking can trigger a serious lung condition called acute chest syndrome.
How can a child have sickle cell anemia if neither parent has it?
Your child would have to inherit two sickle cell genes to have sickle cell disease. So if your child’s father does not have the sickle cell gene, your child can’t get sickle cell disease. But if your child’s father has the sickle cell gene, your child can get sickle cell disease.
How does a person get sickle cell anemia?
It is inherited when a child receives two sickle cell genes—one from each parent. A person with SCD can pass the disease or SCT on to his or her children. How Does Someone Get Sickle Cell Trait? People who have inherited one sickle cell gene and one normal gene have SCT.