Question: Which of the following are used in the formation of a mitotic spindle?

Microtubules consist of polymers of tubulin in dynamic equilibrium with tubulin heterodimers. Their principal function is the formation of the mitotic spindle during cell division, but they are also active in many interphase functions, such as cellular motility, intracellular transport, and signal transmission.

Which of the following is involved in formation of mitotic spindle?

In eukaryotic cells, polymerization of microtubules from alpha and beta tubulin is initiated at the centrosome to form the mitotic spindle and the structure for cytokinesis. During cell division the microtubules continue to polymerize and the mitotic apparatus elongates (Figure 43.10A).

What is a mitotic spindle made of?

The mitotic spindle is the microtubule-based bipolar structure that segregates the chromosomes in mitosis. The poles of the mitotic spindle are made up of centrosomes and the chromosomes are lined up at the spindle equator to ensure their correct bi-orientation and segregation.

What are the 3 major parts of mitotic spindle?

The overall shape of the spindle is framed by three types of spindle microtubules: kinetochore microtubules (green), astral microtubules (blue), and interpolar microtubules (red).

Which of the following is important for spindle Fibre formation?

Spindle fibers are made up of microtubules. Microtubules are polymers of alpha- and beta-tubulin dimers. Microtubules that form the spindle fibers come from centrosomes, which are organelles located in opposite poles near the nucleus.

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Which protein is the major component of mitotic spindle?

Hint: Spindle fibres are composed of a large number of microtubules. It is made up of a single layer of globulin protein. Complete answer: Spindle fibres consist of microtubules that are polymeric chains synthesized from the protein Tubulin.

Is the mitotic spindle made of microtubules?

The segregation of the replicated chromosomes is brought about by a complex cytoskeletal machine with many moving parts—the mitotic spindle. It is constructed from microtubules and their associated proteins, which both pull the daughter chromosomes toward the poles of the spindle and move the poles apart.

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