The genotypes in humans are AA, AS, AC, SS. They refer to the hemoglobin gene constituents on the red blood cells. AC is rare whereas AS and AC are abnormal.
What kind of genotype is AC?
SS and AC are the abnormal genotypes or the sickle cells. We all have a specific pair of these hemoglobin in our blood which we inherited from both parents.
Is AC a sickle cell carrier?
Hemoglobin C disease is not a form of sickle cell disease. People who have hemoglobin C disease have red blood cells that contain mostly hemoglobin C. Too much hemoglobin C can reduce the number and size of red blood cells in your body, causing mild anemia.
Is hemoglobin C sickle cell?
Hemoglobin sickle C disease is a “mild” form of sickle cell anemia. Your child’s red blood cells (RBC’s) contain two abnormal hemoglobins called hemoglobin S and hemoglobin C. Hemoglobin is the substance in the RBC’s which carries oxygen to all parts of the body.
Is AC genotype common in Nigeria?
The World Health Organization also reported that an average of 150,000 infants are born with sickle cell disease in Nigeria. The most commonly encountered abnormal hemoglobin genotypes among Nigerians include AS, AC, SC, and SS.
Can As marry AC?
They refer to the hemoglobin gene constituents on the red blood cells. AC is rare whereas AS and AC are abnormal. Compatible genotypes for marriage are: … AS and AS should not marry, there is every chance of having a child with SS.
What is AC blood type?
A person with hemoglobin C trait makes the usual hemoglobin called A and another hemoglobin called C in his red blood cells. Put the two together in a red blood cell and you have hemoglobin C trait: A and C = AC. Many African Americans have C trait. It is common in people of African origin.
Can 2 sickle cell carriers get married?
When both individuals are sickle cell carriers, the church discourages them from marrying. Some church denominations, especially in Enugu state, go further and refuse to wed couples when both individuals are sickle cell carriers.
Can a man with sickle cell have a baby?
Infertility seems to be a greater problem among males than females with sickle cell disease, because such men rarely have fathered children, whereas many women with sickle cell disease have had sucessful pregnancies.
What is AC trait?
Hemoglobin C trait (AC) is an inherited condition which affects the hemoglobin in your red blood cells. • Hemoglobin is a protein in red blood cells. The job of hemoglobin is. to carry oxygen throughout the body.
What blood type carries sickle cell?
It is an inherited condition in which both hemoglobin A and S are produced in the red blood cells, always more A than S. Individuals with sickle cell trait are generally healthy.
What does hemoglobin S stand for?
Hemoglobin S (Hgb S) is an abnormal type of hemoglobin that you can inherit from your parents. Hgb S causes red blood cells to become stiff and abnormally shaped. Instead of having a normal round, disk shape, these red blood cells become sickle-shaped, or crescent-shaped.
What is SS genotype?
Hemoglobin SS disease is the most common type of sickle cell disease. It occurs when you inherit copies of the hemoglobin S gene from both parents. This forms hemoglobin known as Hb SS. As the most severe form of SCD, individuals with this form also experience the worst symptoms at a higher rate.