Are sister chromatids pulled apart?

In metaphase (a), the microtubules of the spindle (white) have attached and the chromosomes have lined up on the metaphase plate. During anaphase (b), the sister chromatids are pulled apart and move toward opposite poles of the cell.

Why do the sister chromatids need to be pulled apart?

Separation of sister chromatids during mitosis is a potential danger point for a cell. After DNA is replicated each chromosome consists of paired sister chromatids held together by cohesin. Therefore, if the DNA is damaged, the cell can use information present in the undamaged chromatid to guide the repair process.

Why do sister chromatids separate in anaphase 2?

Anaphase II is the stage when sister chromatids of every chromosome separate and begin to move towards the opposite ends of the cell. The separation and the movement is due to the shortening of the kinetochore microtubules.

Why do sister chromatids separate in anaphase?

The sister chromatids are pairs of identical copies of DNA joined at a point called the centromere. During anaphase, each pair of chromosomes is separated into two identical, independent chromosomes. … The separated chromosomes are then pulled by the spindle to opposite poles of the cell.

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What happens when spindle fibers don’t form?

Spindle fiber formation occurs but spindle fibers cannot function properly, i.e. they cannot separate the daughter chromosomes in the division process. … Chromosomes clump in several areas of the cell rather than along the single metaphase plate. Mitosis is disrupted and growth increases.

What would happen if sister chromatids were not pulled apart at anaphase II?

If sister chromatids do not split equally during anaphase of mitosis, one daughter cell would have more chromosomes than normal and one daughter cell

What happens if both sister chromatids move to the same pole during mitosis?

The first round of chromosome segregation (meiosis I) is unique in that sister chromatids move together to the same spindle pole while homologous chromosomes move apart from each other to the opposite poles. … This leads to the formation of chiasmata, which maintain homolog association until the onset of anaphase I.

What is the role of sister chromatids?

The sister chromatid cohesion apparatus mediates physical pairing of duplicated chromosomes. This pairing is essential for appropriate distribution of chromosomes into the daughter cells upon cell division.

Why do sister chromatids remain attached in anaphase 1?

The bivalents, which are attached to microtubules through their kinetochores and centromeres, align on the metaphase plate during metaphase I. Unlike in mitosis, the sister chromatids remain attached at their centromeres by cohesion, and only the homologous chromosomes segregate during anaphase I.

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