What is the significance of giant chromosome?

The interbands are involved in the interaction with the active chromatin proteins, nucleosome remodeling, and origin recognition complexes. Their primary functions are: to act as binding sites for RNA pol II, to initiate replication and, to start nucleosome remodeling of short fragments of DNA.

Do humans have giant chromosomes?

Polytene chromosomes are formed when the products of multiple rounds of S-phase remain tightly associated to form one supersized chromosome. … We also note that polytene chromosomes can form in cells that undergo transient nuclear envelope breakdown without subsequent chromosome separation (Cantero et al.

What are Balbiani rings?

Balbiani rings are exceptionally large puffs on the polytene chromosomes in the dipteran Chironomus tentans. These puffs are particularly well suited for studies of the structure of active genes and the synthesis and transport of specific RNA-protein (RNP) particles.

What is the function of Lampbrush chromosome?

Lampbrush chromosomes are also involved in the production of “masked” mRNAs for early development. The giant granular loops could either be the sites where such mRNAs are packaged or they could be sites where specific alterations of the deoxyribonucleoprotein fiber take place.

Who discovered giant chromosome?

They were first observed in 1881 by E.G. Balbiani in Chironomus and were studied by Korschelt (1884) and Corney (1884). Heitz and Bauer in 1933 studied these giant chromosomes in Bibio hortulanus larvae, while Painter (1933) described them in salivary glands of Drosophila.

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What is the meaning of Chromomere?

: one of the small bead-shaped and heavily staining masses of coiled chromatin that are linearly arranged along the chromosome.

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