Whats the definition of telomere?
(TEH-loh-meer) The ends of a chromosome. Each time a cell divides, the telomeres lose a small amount of DNA and become shorter. Over time, the chromosomes become damaged and the cells die. In cancer cells the telomeres do not get shorter, and may become longer, as the cells divide.
What type of DNA is telomere?
Telomere, segment of DNA occurring at the ends of chromosomes in eukaryotic cells (cells containing a clearly defined nucleus). Telomeres are made up of repeated segments of DNA that consist of the sequence 5′-TTAGGG-3′ (in which T, A, and G are the bases thymine, adenine, and guanine, respectively).
Is telomerase good or bad?
Too much telomerase can help confer immortality onto cancer cells and actually increase the likelihood of cancer, whereas too little telomerase can also increase cancer by depleting the healthy regenerative potential of the body.
Can telomerase reverse aging?
An enzyme called telomerase can slow, stop or perhaps even reverse the telomere shortening that happens as we age. The amount of telomerase in our bodies declines as we age.
What food contains telomerase?
Telomere length is positively associated with the consumption of legumes, nuts, seaweed, fruits, and 100% fruit juice, dairy products, and coffee, whereas it is inversely associated with consumption of alcohol, red meat, or processed meat [27,28,33,34].
What would happen if we didn’t have telomeres?
They protect the ends of our chromosomes by forming a cap, much like the plastic tip on shoelaces. If the telomeres were not there, our chromosomes may end up sticking to other chromosomes. … Without telomeres, important DNA would be lost every time a cell divides (usually about 50 to 70 times).
What happens if telomeres are too long?
It was known that very short telomeres cause harm to a cell. But what was totally unexpected was our finding that damage also occurs when telomeres are very long.” … As telomeres shorten over time, the chromosomes themselves become vulnerable to damage. Eventually the cells die.
What is telomerase activity?
Telomerase is the enzyme responsible for maintenance of the length of telomeres by addition of guanine-rich repetitive sequences. Telomerase activity is exhibited in gametes and stem and tumor cells. … Besides catalytic telomere elongation, independent telomerase functions can be also involved in cell cycle regulation.