|Class of Mutation||Type of Mutation||Human Disease(s) Linked to This Mutation|
|Chromosomal mutation||Deletion||Cri du chat syndrome|
|Translocation||One form of leukemia|
|Copy number variation||Gene amplification||Some breast cancers|
What is a chromosomal mutation?
Chromosome mutation is the process of change that results in rearranged chromosome parts, abnormal numbers of individual chromosomes, or abnormal numbers of chromosome sets.
What are the 5 chromosome mutations?
Changes to chromosome 5 include an extra segment of the short (p) or long (q) arm of the chromosome in each cell (partial trisomy 5p or 5q), a missing segment of the long arm of the chromosome in each cell (partial monosomy 5q), and a circular structure called ring chromosome 5.
What is the difference between chromosomal and gene mutation?
A person can have normal chromosomes in number and structure, but still have a disease or condition caused by a mutation in one or more of the genes on the chromosomes. A single gene defect usually does not cause the chromosome structure or number to be abnormal.
What are the two major types of mutations?
Two major categories of mutations are germline mutations and somatic mutations. Germline mutations occur in gametes. These mutations are especially significant because they can be transmitted to offspring and every cell in the offspring will have the mutation.
What are the main types chromosomal mutations?
Chromosome structure mutations can be one of four types:
- deletion is where a section of a chromosome is removed.
- translocation is where a section of a chromosome is added to another chromosome that is not its homologous partner.
- inversion is where a section of a chromosome is reversed.
What kind of mutation is more likely to result in?
A point mutation could be a silent mutation, maintaining the original amino acid sequence and the resulting protein. A frameshift mutation is more likely to result in a nonfunctional protein.
What are the four type of mutations?
In Summary: Major Types of Mutations
Mutations can be of many types, such as substitution, deletion, insertion, and translocation.
What is a silent mutation?
A mutation where a change in a DNA codon does not result in a change in amino acid translation.
What causes mutation?
Mutation. A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during cell division, exposure to ionizing radiation, exposure to chemicals called mutagens, or infection by viruses.