|No. of genes||1,224 (CCDS)|
|Centromere position||Submetacentric (53.4 Mbp)|
|Complete gene lists|
Where is chromosome 11 in the body?
Chromosome 11 contains two clusters of imprinted genes (see Fig. 2), both located in the 11p15. 5 region, but regulated by separate imprinting control regions (ICRs). The more telomeric of the two ICRs, ICR1, controls expression of the reciprocally imprinted IGF2 (insulin-like growth factor type 2) and H19 loci.
How many genes does chromosome 11 have?
The scientists found that chromosome 11 contains more than 1,500 genes, placing it the fourth highest among all of the human chromosomes in gene content.
Is chromosome 11 a gene?
Chromosome 11, although average in size, is one of the most gene- and disease-rich chromosomes in the human genome. Initial gene annotation indicates an average gene density of 11.6 genes per megabase, including 1,524 protein-coding genes, some of which were identified using novel methods, and 765 pseudogenes.
What happens if you have 11 chromosomes?
Signs & Symptoms
Chromosome 11, Partial Trisomy 11q is commonly characterized by growth retardation before and after birth, delayed acquisition of skills requiring the coordination of mental and motor activities (psychomotor retardation), mild to moderate mental retardation, and distinctive craniofacial abnormalities.
What does the 12 chromosome do?
Chromosome 12 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 12 spans about 133 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the total DNA in cells.
What is the most important chromosome?
Chromosome 1 is the largest human chromosome, spanning about 249 million DNA building blocks (base pairs) and representing approximately 8 percent of the total DNA in cells. Identifying genes on each chromosome is an active area of genetic research.
What is the most common syndrome?
Down syndrome is the most commonly diagnosed chromosomal disorder, which affects 1 in every 691 babies born in the United States. Individuals with Down syndrome have a defect in chromosome 21.
What is Paris Trousseau syndrome?
Definition. Paris-Trousseau thrombocytopenia (TCPT) is a contiguous gene syndrome characterized by mild bleeding tendency, variable thrombocytopenia (THC), dysmorphic facies, abnormal giant alpha-granules in platelets and dysmegakaryopoiesis.
What chromosome is albinism on?
The most common form is type 1, inherited by a gene mutation on the X chromosome. X-linked ocular albinism can be passed on by a mother who carries one mutated X gene to her son (X-linked recessive inheritance).
What are chromosome 2 traits?
Individuals with this chromosome abnormality often have developmental delay, small head size (microcephaly), slow growth before and after birth, heart defects, and distinctive facial features. The severity of symptoms typically depends on how many and which types of cells contain the ring chromosome 2.