Is Down syndrome associated with infertility?

While females with Down syndrome are reported to be fertile or subfertile, males are reported to be infertile. To date, there are reports of three pregnancies that were fathered by two male Down syndrome patients (1, 2). We report a case of a nonmosaic Down syndrome male who fathered a normal child.

Is infertility a symptom of Down syndrome?

Men with Down syndrome are considered as infertile although the causes of infertility are not known in detail yet. Although this constitutes a general rule there are three confirmed cases of parenting by fathers with Down syndrome.

How does Down syndrome affect fertility?

Therefore, prenatal screening and genetic counseling are important. People with Down syndrome rarely reproduce. Fifteen to thirty percent of women with trisomy 21 are fertile and they have about a 50% risk of having a child with Down syndrome. There is no evidence of a man with Down syndrome fathering a child.

Can a male with Down syndrome father a child?

Most men with Down syndrome cannot father a child. In any pregnancy, a woman with Down syndrome has a 1 in 2 chance of conceiving a child with Down syndrome. Many of the pregnancies are miscarried.

Can a Down syndrome child look normal?

Some of the children with Mosaic Down syndrome that we know do not actually look as if they have Down syndrome – the usual physical features are not obvious. This raises some important and difficult social issues and identity issues for both parents and children, which parents have discussed with us.

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What gender does Down syndrome affect most?

Down syndrome appears to be more common among boys than girls, the study indicates. The condition is also seen more frequently in Hispanic children at birth, though the number of these children appears to level off with that of white children as they age. Black children appear less likely to have Down syndrome.

Can you tell if a baby has Down syndrome in an ultrasound?

An ultrasound can detect fluid at the back of a fetus’s neck, which sometimes indicates Down syndrome. The ultrasound test is called measurement of nuchal translucency.

What is the root cause of Down syndrome?

Down syndrome is caused by a random error in cell division that results in the presence of an extra copy of chromosome 21. The type of error is called nondisjunction (pronounced non-dis-JUHNGK-shuhn).

Can 2 Down syndrome have a baby?

Any couple can have a baby with Down’s syndrome, but it is well known that older women are more likely to have a baby with the condition than younger women. There is controversy about the influence of the father’s age.

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