How does Down’s syndrome affect the brain?

We know that people with Down syndrome have difficulties with brain function, including problems with learning, memory and speech throughout life, as well as the onset in later life of increased cognitive problems associated with the brain changes of Alzheimer’s disease.

What parts of the brain is affected by Down syndrome?

Our preliminary findings suggest that people with DS have decreases in the volume of gray and white matter in the frontal lobes and cerebellum. These findings are interesting since the frontal lobes are thought to perform roles in language and memory.

Does Down syndrome affect thinking?

Down syndrome causes physical, cognitive (thinking) and behavioral symptoms. Physical signs of Down syndrome can include: Short, stocky physical size, with a short neck. Poor muscle tone.

How Are Down syndrome brains different?

Our findings indicate that compared to matched developmentally normal subjects, the brains of individuals with Down’s syndrome show 1) overall smaller volumes due to smaller volumes of both cerebral gray and white matter, 2) a disproportionately smaller cerebellar volume, and 3) larger adjusted volumes of subcortical …

Can a Down syndrome child look normal?

Some of the children with Mosaic Down syndrome that we know do not actually look as if they have Down syndrome – the usual physical features are not obvious. This raises some important and difficult social issues and identity issues for both parents and children, which parents have discussed with us.

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Does Down syndrome get worse with age?

Adults with Down syndrome experience “accelerated aging,” meaning they will age faster than the general population. It is expected that adults with Down syndrome will show physical, medical, and cognitive signs of aging much earlier than what is expected for their age.

Why is Down syndrome not curable?

Down syndrome is a random occurrence in nature. It has no cure or prevention measures. Down syndrome is not a disease, disorder, defect or medical condition and therefore does not require treatment, prevention or a cure.

Can MRI detect Down syndrome?

Individuals with Down syndrome (DS), a disorder of known genetic etiology (trisomy of chromosome 21), exhibit several types of structural brain abnormalities that are detectable pathologically and by MRI.

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