Frequent question: Is Klinefelter syndrome Down syndrome?

In conclusion, Down–Klinefelter’s syndrome is a rare chromosomal abnormality. Patient present with physical characteristics of Down’s syndrome at birth and Klinefelter’s syndrome features at during puberty.

What is Down syndrome and Klinefelter syndrome attributed to?

In 1959, Down syndrome was shown to be associated with an extra chromosome in the G group1; Klinefelter syndrome was associated with an extra X chromosome2; and a case of double aneuploidy, a 48,XXY,G + male, was reported.

What gender is Klinefelter syndrome?

Klinefelter syndrome is a genetic condition affecting males, and it often isn’t diagnosed until adulthood.

What is the survival rate of Klinefelter syndrome?

We found that Klinefelter syndrome was associated with a significant increase in mortality risk of 40% (hazard ratio, 1.40; 95% confidence interval, 1.13-1.74), corresponding to a significantly reduced median survival of 2.1 yr.

What are the chances of having a child with Klinefelter syndrome?

It is estimated that 1 in every 500 to 1,000 newborn males has an extra X chromosome, making Klinefelter syndrome one of the most common chromosomal disorders seen among newborns. Variants of Klinefelter syndrome (such as 48,XXXY, 49,XXXXY) are much rarer, occurring in 1 in 50,000 to 1 in 85,000 or fewer newborns.

What is the difference between Klinefelter’s syndrome and Turner’s syndrome?

The most common are Klinefelter syndrome (KS), resulting from the gain of an X chromosome in males, and Turner syndrome (TS), reflecting the loss of an X chromosome or the presence of a structurally different X chromosome in females.

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What is super male syndrome?

XYY syndrome is a rare chromosomal disorder that affects males. It is caused by the presence of an extra Y chromosome. Males normally have one X and one Y chromosome. However, individuals with this syndrome have one X and two Y chromosomes. Affected individuals are usually very tall.

What is difference between Down syndrome and Turner syndrome?

Turner syndrome is caused by complete or partial X monosomy. The incidence of Turner syndrome is approximately 1 in 2000 among live female infants. In contrast to Down syndrome, there is no association between Turner syndrome and advanced maternal age [27].

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