The telomeres of most laboratory mice are 5 to 10 times longer than in humans, but their lifespan is 30 times shorter.
Do mice express telomerase?
Compared to humans, telomere homeostasis in mice is distinctive in two ways: Laboratory mice express ubiquitous telomerase activities in somatic tissues and possess long heterogeneous telomeres. There exist significant differences in telomerase expression between humans and mice.
What foods help telomeres?
Telomere length is positively associated with the consumption of legumes, nuts, seaweed, fruits, and 100% fruit juice, dairy products, and coffee, whereas it is inversely associated with consumption of alcohol, red meat, or processed meat [27,28,33,34].
How do you stop telomerase?
Dietary restriction, appropriate diet (high fiber, plenty of antioxidants, lean/low protein, adding soy protein to diet), and regular exercise can potentially reduce the rate of telomere shortening, disease risk, and pace of aging.
What increases telomere length?
Research shows that those with higher levels of antioxidants such as Vitamin C, E and selenium tend to have longer telomeres. Fruits and vegetables are the best sources of antioxidants, which is why a plant-based diet is highly recommended.
What is the best supplement for telomeres?
Vitamin D promotes activity of telomerase, the repair enzyme that steadily adds to telomere length. Vitamins C and E preserve telomere length by reducing the chemical stresses that contribute to telomere shortening. Gamma-tocotrienol in particular may reverse telomere shortening and attendant cellular aging.
Do lab mice have longer telomeres than wild mice?
(It’s true that wild mice have shorter telomeres than lab mice, but they are no shorter than human telomeres.)